A study that achieves the possibility of producing low-cost medicine in lettuce leaves

Scientists at the University of Pennsylvania have discovered a new way to produce a drug in lettuce leaves that is effective in the treatment of hemophilia. The study of drug production has had a significant impact because it has provided large and sufficient quantities of medicine at a lower cost. It has been shown in a previous study that the production of protein within the leaves of the plant genetically modified tobacco helps the immune system to tolerate external clotting factors, which is the basic treatment of hemophilia. It is known that "20% -30%" of patients are their bodies form antibodies to external clotting factors. In fact, the protein produced in the experiment succeeded in mice infected with hemophilia A and prevented the formation of antibodies to clotting factors. In the previous study, scientists used the tobacco plant in their research, while scientists at the University of Pennsylvania realized that in order for clinical trials to be carried out on humans, the tobacco plant should be replaced and the lettuce plant was chosen as an alternative. In addition, scientists have had to use a different vector to transfer the gene to the DNA of lettuce leaves, since it differs from the tobacco plant.

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